Recombinant Treponema pallidum p15 (Syphilis)

Short term store at 2–8oC. Long term store, at -20°C. Avoid multiple freeze/thaw cycles.

The, complete genome sequence of Treponema pallidum has been determined and shown, to be 1, 138, 006 base pairs containing 1041 predicted coding sequences (open, reading frames). Systems for DNA replication, transcription, translation, and, repair are intact, but catabolic and biosynthetic activities are minimized. Treponema, pallidum is a gram-negative spirochaete bacterium and there are at least four, known subspecies: T. pallidum pallidum, which causes syphilis, T. pallidum, pertenue, which causes yaws, T. pallidum carateum, which causes pinta, and T. pallidum endemicum, which causes bejel. There is no vaccine for syphilis. The, outer membrane of T. pallidum has too few surface proteins for an antibody to, be effective. Efforts to develop a safe and effective syphilis vaccine have, been hindered by uncertainty about the relative importance of humoral and, cellular mechanisms to protective immunity and the fact that T. pallidum, outer membrane proteins have not been unambiguously identified.

Purified, Liquid

4.59mg/ml