GLB1 Antibody

Polyclonal Antibody

GLB1

Acid beta galactosidase antibody, Acid beta-galactosidase antibody, Beta galactosidase 1 antibody, Beta galactosidase antibody, Beta-galactosidase antibody, BGAL_HUMAN antibody, EBP antibody, EBP, included antibody, Elastin receptor 1 (67kD) antibody, Elastin receptor 1 67kDa antibody, Elastin receptor 1 antibody, Elastin receptor 1, included antibody, Elastin-binding protein, included antibody, ELNR1 antibody, Galactosidase beta 1 antibody, GLB 1 antibody, GLB1 antibody, Lactase antibody, MPS4B antibody, S-GAL, included antibody

Synthesized peptide derived from internal of human GLB1.

Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. soform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.

Oshima A., Biochem. Biophys. Res. Commun. 157:238-244(1988) [PubMed: 3143362].
Morreau H., J. Biol. Chem. 264:20655-20663(1989) [PubMed: 2511208].
Yamamoto Y., DNA Cell Biol. 9:119-127(1990) [PubMed: 2111707].

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Signal Transduction

Synthesized peptide derived from internal of Human GLB1.