ArtNr |
CSB-PA618970LC01HU |
Hersteller |
Cusabio
|
Menge |
100ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Pre-mRNA-splicing regulator WTAP,Female-lethal(2)D homolog,hFL(2)D,WT1-associated protein,Wilms tumor 1-associating protein,WTAP,KIAA0105 |
Lieferbar |
|
Background |
Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). |
Alias |
Pre-mRNA-splicing regulator WTAP, Female-lethal(2)D homolog, hFL(2)D, WT1-associated protein, Wilms tumor 1-associating protein, WTAP, KIAA0105 |
Uniprot |
Q15007 |
Immuongen |
Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA) |
Counjugation |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
>95%, Protein G purified |
Abbreviation |
Pre-mRNA-splicing regulator WTAP |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.