ArtNr |
CSB-PA883623LC01HU |
Hersteller |
Cusabio
|
Menge |
100ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human (Homo sapiens) |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
C-type lectin domain family 7 member A,Beta-glucan receptor,C-type lectin superfamily member 12,Dendritic cell-associated C-type lectin 1,DC-associated C-type lectin 1,Dectin-1,CLEC7A,BGR,CLECSF12,DECTIN1,UNQ539/PRO1082 |
Lieferbar |
|
Background |
Lectin that functions as pattern receptor specific for beta-1, 3-linked and beta-1, 6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity). |
Alias |
C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, BGR, CLECSF12, DECTIN1, UNQ539/PRO1082 |
Uniprot |
Q9BXN2 |
Immuongen |
Recombinant Human C-type lectin domain family 7 member A protein (1-44AA) |
Counjugation |
FITC |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
>95%, Protein G purified |
Abbreviation |
C-type lectin domain family 7 member A |
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