TAOK3 Antibody

Polyclonal Antibody

TAOK3

CTCL tumor antigen HD CL 09 antibody, CTCL-associated antigen HD-CL-09 antibody, Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody, Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody, Dendritic cell derived protein kinase antibody, Dendritic cell-derived protein kinase antibody, DKFZp666H245 antibody, DPK antibody, FLJ31808 antibody, hKFC A antibody, hKFC-A antibody, JIK antibody, JNK/SAPK inhibitory kinase antibody, JNK/SAPK-inhibitory kinase antibody, Jun kinase inhibitory kinase antibody, Jun kinase-inhibitory kinase antibody, KDS antibody, Kinase from chicken homolog A antibody, MAP3K18 antibody, Serine kinase antibody, Serine/threonine-protein kinase TAO3 antibody, STE20 like kinase antibody, TAO kinase 3 antibody, TAOK3 antibody, TAOK3_HUMAN antibody, Thousand and one amino acid protein 3 antibody

Synthesized peptide derived from internal of human TAOK3.

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

Tassi E., J. Biol. Chem. 274:33287-33295(1999).
Zhang W., Biochem. Biophys. Res. Commun. 274:872-879(2000).
Yustein J.T., Oncogene 22:6129-6141(2003).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Signal Transduction

Synthesized peptide derived from internal of Human TAOK3.