LAMB1 Antibody

Polyclonal Antibody

LAMB1

CLM antibody, Cutis laxa with marfanoid phenotype antibody, LAM B1 antibody, LAMB 1 antibody, LAMB1 antibody, LAMB1_HUMAN antibody, Laminin B1 antibody, Laminin B1 chain antibody, Laminin beta 1 chain antibody, Laminin beta 1 chain precursor antibody, Laminin beta1 antibody, Laminin subunit beta 1 antibody, Laminin subunit beta-1 antibody, Laminin-1 subunit beta antibody, Laminin-10 subunit beta antibody, Laminin-12 subunit beta antibody, Laminin-2 subunit beta antibody, Laminin-6 subunit beta antibody, Laminin-8 subunit beta antibody, LIS5 antibody, MGC142015 antibody

Synthesized peptide derived from C-terminal of human LAMB1.

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

Vuolteenaho R., J. Biol. Chem. 265:15611-15616(1990).
Pikkarainen T., J. Biol. Chem. 262:10454-10462(1987).
Scherer S.W., Science 300:767-772(2003).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cardiovascular

Synthesized peptide derived from C-terminal of Human LAMB1.