CYP1B1 Antibody

ArtNr	CSB-PA006397KA01HU
Hersteller	Cusabio
Menge	100 ul
Kategorie	Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Aryl hydrocarbon hydroxylase antibody,CP1B antibody,CP1B1_HUMAN antibody,Cyp1b1 antibody,CYPIB1 antibody,Cytochrome P450 1B1 antibody,Cytochrome P450 family 1 subfamily B polypeptide 1 antibody,Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody,Flavoprotein linked monooxygenase antibody,GLC3A antibody,Microsomal monooxygenase antibody,P4501B1 antibody,Xenobiotic monooxygenase antibody
Similar products	CYP1B1, CP1B, GLC3A, P4501B1
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200
Manufacturer - Targets	CYP1B1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Aryl hydrocarbon hydroxylase antibody, CP1B antibody, CP1B1_HUMAN antibody, Cyp1b1 antibody, CYPIB1 antibody, Cytochrome P450 1B1 antibody, Cytochrome P450 family 1 subfamily B polypeptide 1 antibody, Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody, Flavoprotein linked monooxygenase antibody, GLC3A antibody, Microsomal monooxygenase antibody, P4501B1 antibody, Xenobiotic monooxygenase antibody
Immunogen Species	Human
Immunogen	Recombinant protein of human CYP1B1
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:2000 IHC:1:50-1:200
Background	Cytochrome P450 1B1 (CYP1B1) is a key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental carcinogens and is the predominant member of the CYP1 family expressed in normal breast tissue and breast cancer. Estrogen has been proposed to trigger breast cancer development via an initiating mechanism involving its metabolite, catechol estrogen (CE). CYP1B1 catalyzes the conversion of 17-beta-estradiol to the catechol estrogen metabolites 2-OH-E2 and 4-OH-E2 which have both been postulated to be involved in mammary carcinogenesis. Genetic polymorphisms in CYP1B1 may play an important role in human prostate carcinogenesis as well. Polymorphism of the CYP1B1 gene at codon 432 (Val-->Leu) is associated with a change in catalytic function.
Buffer	Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity-chromatography purified
General Research Areas	Cardiovascular
Initial Research Areas	Cardiovascular
Antigen Species	Human
Antigen	Recombinant protein of Human CYP1B1
Clonality	Polyclonal

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Menge: 100 ul

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Lieferung vsl. bis 22.01.2026

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