CDKN1B (Ab-10) Antibody

Polyclonal Antibody

CDKN1B

AA408329 antibody, AI843786 antibody, Cdki1b antibody, CDKN 1B antibody, CDKN 4 antibody, CDKN1B antibody, CDKN4 antibody, CDN1B_HUMAN antibody, Cyclin Dependent Kinase Inhibitor 1B antibody, Cyclin dependent kinase inhibitor p27 antibody, Cyclin-dependent kinase inhibitor 1B (p27, Kip1) antibody, Cyclin-dependent kinase inhibitor 1B antibody, Cyclin-dependent kinase inhibitor p27 antibody, Cyclin-dependent kinase inhibitor p27 Kip1 antibody, KIP 1 antibody, KIP1 antibody, MEN1B antibody, MEN4 antibody, OTTHUMP00000195098 antibody, OTTHUMP00000195099 antibody, p27 antibody, p27 Kip1 antibody, P27-like cyclin-dependent kinase inhibitor antibody, p27Kip1 antibody

Peptide sequence around aa.8ca.12 (N-G-S-P-S) derived from Human p27Kip1.

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Positive regulator of cyclin D-dependent kinases such as CDK4. Regulated by phosphorylation and degradation events.

Le XF, et al. (2003)J Biol Chem.
Connor MK, et al. (2003)Mol Biol Cell, 14(1): 201-13.
McAllister SS, et al. (2003) Mol Cell Biol, 23(1): 216-28.
Chopra S, et al. (2002)J Biol Chem, 277(36): 32413-6.
Boehm M, et al. (2002)EMBO J, 21(13): 3390-401.

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Cell Biology

Peptide sequence around aa.8~12 (N-G-S-P-S) derived from Human p27Kip1.