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ADRBK1 (Ab-86) Antibody

ADRBK1 (Ab-86) Antibody

ArtNr	CSB-PA122053
Hersteller	Cusabio
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot ELISA Cardiovascular Research Heart Failure Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ADRBK1 antibody; Adrenergic beta receptor kinase 1 antibody; ARBK1_HUMAN antibody; BARK antibody; BARK1 antibody; Beta adrenergic receptor kinase 1 antibody; Beta ARK 1 antibody; Beta ARK1 antibody; Beta-adrenergic receptor kinase 1 antibody; Beta-ARK-1 antibody; FLJ16718 antibody; G protein coupled receptor kinase 2 antibody; G-protein coupled receptor kinase 2 antibody; GRK2 antibody
Similar products	ADRBK1, beta, adrenergic, ARBK1, receptor kinase 1
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	GRK2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	ADRBK1 antibody; Adrenergic beta receptor kinase 1 antibody; ARBK1_HUMAN antibody; BARK antibody; BARK1 antibody; Beta adrenergic receptor kinase 1 antibody; Beta ARK 1 antibody; Beta ARK1 antibody; Beta-adrenergic receptor kinase 1 antibody; Beta-ARK-1 antibody; FLJ16718 antibody; G protein coupled receptor kinase 2 antibody; G-protein coupled receptor kinase 2 antibody; GRK2 antibody
Immunogen Species	Human
Immunogen	Synthesized peptide derived from N-terminal of human ADRBK1.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:3000
Background	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Benovic J.L., FEBS Lett. 283:122-126(1991). Chuang T.T., J. Biol. Chem. 267:6886-6892(1992). Penn R.B., J. Biol. Chem. 269:14924-14930(1994).
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Synthesized peptide derived from N-terminal of Human ADRBK1.
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 11.09.2025

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