Phospho-MYOD1 (Ser200) Antibody

Polyclonal Antibody

MYOD1

bHLHc1 antibody, Class C basic helix-loop-helix protein 1 antibody, MYF 3 antibody, Myf-3 antibody, MYF3 antibody, Myoblast determination protein 1 antibody, Myod 1 antibody, MYOD antibody, MYOD1 antibody, MYOD1_HUMAN antibody, Myogenic differentiation 1 antibody, Myogenic factor 3 antibody, Myogenic factor MYF 3 antibody, Myogenin D1 antibody, PUM antibody

Peptide sequence around phosphorylation site of serine 200 (A-S-S(p)-P-R) derived from Human MyoD.

MyoD encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and themyogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite formyogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis.

Emmanuel G, et al. J. Biol. Chem., Jun 2000, 275: 18767 - 18776
Tintignac LA, et al. Mol Cell Biol. 2004 Feb, 24(4): 1809-1821.
Kitzmann M, et a. Mol Cell Biol. 1999 Apr, 19(4): 3167-3176.

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Epigenetics and Nuclear Signaling

Peptide sequence around phosphorylation site of serine 200 (A-S-S(p)-P-R) derived from Human MyoD.