EIF4E (Ab-209) Antibody

EIF4E

AUTS19 antibody; CBP antibody; eIF 4E antibody; eIF 4F 25 kDa subunit antibody; EIF 4F antibody; eIF-4E antibody; eIF-4F 25 kDa subunit antibody; eIF4E antibody; EIF4E1 antibody; EIF4EL1 antibody; EIF4F antibody; Eukaryotic translation initiation factor 4 E antibody; Eukaryotic translation initiation factor 4E antibody; Eukaryotic translation initiation factor 4E like 1 antibody; IF4E_HUMAN antibody; Messanger RNA Cap Binding Protein eIF 4E antibody; MGC111573 antibody; mRNA cap binding protein antibody; mRNA cap-binding protein antibody

Peptide sequence around aa. 207ca.211 (S-G-S-T-T) derived from Human eIF4E.

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Li BD, et al. (1998) Ann Surg, 227(5): 756-763
Altmann M, et al. (1989) Nucleic Acids Res, 17(18): 7520
De Gregorio E, et al. (2001) RNA, 7(1): 106-113
Gu W, et al. (2004) Nucleic Acids Res, 32(15): 4448-4461
Ohlmann T, et al. (1996) EMBO J, 15(6): 1371-1382

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugateds. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Epigenetics and Nuclear Signaling

Peptide sequence around aa. 207~211 (S-G-S-T-T) derived from Human eIF4E.