Phospho-FLT1 (Tyr1213) Antibody

FLT1

EC 2.7.10.1 antibody; FLT 1 antibody; FLT antibody; Flt-1 antibody; FLT1 antibody; Fms like tyrosine kinase 1 antibody; Fms related tyrosine kinase 1 antibody; Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody; Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody; Fms-like tyrosine kinase 1 antibody; FRT antibody; Soluble VEGF receptor 1 14 antibody; Soluble VEGFR1 variant 2 antibody; Soluble VEGFR1 variant 21 antibody; Tyrosine protein kinase FRT antibody; Tyrosine protein kinase receptor FLT antibody; Tyrosine-protein kinase FRT antibody; Tyrosine-protein kinase receptor FLT antibody; Vascular endothelial growth factor receptor 1 antibody; Vascular endothelial growth factor vascular permeability factor receptor antibody; Vascular permeability factor receptor 1 antibody; Vascular permeability factor receptor antibody; VEGFR 1 antibody; VEGFR-1 antibody; VEGFR1 antibody; VGFR1_HUMAN antibody

Peptide sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

Raghu H, et al. (2012) Mol Oncol 6, 33-47
Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54
Ito N, Wernstedt C, Engstr m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugateds. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Cardiovascular

Peptide sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.