HDAC10 Antibody

ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Synthesized peptide derived from human HDAC10.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Jenny J. Tong, Nucleic Acids Res., Mar 2002, 30: 1114 - 1123.
Hung-Ying Kao, J. Biol. Chem., Jan 2002, 277: 187 - 193.
Denise D. Fischer, J. Biol. Chem., Feb 2002, 277: 6656 - 6666.
Matthew H. Brush, J. Biol. Chem., Feb 2004, 279: 7685 - 7691.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Epigenetics and Nuclear Signaling

Synthesized peptide derived from Human HDAC10.