RPS4X Antibody

P62701

ELISA, WB, IF, WB:1:500-1:3000, IF:1:100-1:500

WB:1:500-1:3000

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome, however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Fisher E.M.C., Cell 63:1205-1218(1990).
Watanabe M., J. Cell Sci. 100:35-43(1991).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

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