MME Antibody

Polyclonal Antibody

MME

Atriopeptidase antibody, CALLA antibody, CD10 antibody, CD10 antigen antibody, Common acute lymphocytic leukemia antigen antibody, DKFZp686O16152 antibody, EC 3.4.24.11 antibody, Enkephalinase antibody, EPN antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody, Membrane metallo endopeptidase antibody, Membrane metallo endopeptidase variant 1 antibody, Membrane metallo endopeptidase variant 2 antibody, Membrane metalloendopeptidase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody, Membrane metalloendopeptidase variant 1 antibody, Membrane metalloendopeptidase variant 2 antibody, MGC126681 antibody, MGC126707 antibody, MME antibody, NEP antibody, NEP_HUMAN antibody, Neprilysin antibody, neprilysin-390 antibody, neprilysin-411 antibody, Neutral endopeptidase 24.11 antibody, Neutral endopeptidase antibody, Neutral endopeptidase, membrane-associated antibody, SFE antibody, Skin fibroblast elastase antibody

Peptide sequence around aa.6ca.10(S-Q-M-D-I) derived from Human CD10.

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Yandle T.G., Brennan S.O., Espiner E.A., Nicholls M.G., Richards A.M.Peptides 10:891-894(1989)
Rice G.I., Thomas D.A., Grant P.J., Turner A.J., Hooper N.M.Biochem. J. 383:45-51(2004)
Morisaki N., Moriwaki S., Sugiyama-Nakagiri Y., Haketa K., Takema Y., Imokawa G.J. Biol. Chem. 285:39819-39827(2010)

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunology

Human

Polyclonal