Recombinant Human Prostaglandin G/H synthase 2(PTGS2),partial

Metabolism

PTGS2

ANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGE NCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNV VNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGY KSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQL PDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFT HQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQ RKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYP PQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNR VCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIE DYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEF NTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLE HGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQAS IDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKE MSAELEALYGDIDAVELYPALLVEKPRPDAIFGET MVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGF QIINTASIQSLICNNVKGCPFTSFSVPDPELIKTV TINASSSRSGLDDINPTVLLKERS

Partial

N-terminal 6xHis-tagged

Cyclooxygenase-2 ; COX-2; PHS IIProstaglandin H2 synthase 2 ; PGH synthase 2 ; PGHS-2; Prostaglandin-endoperoxide synthase 2

The DNA sequence and biological annotation of human chromosome 1.Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.Nature 441:315-321(2006)

Tris-based buffer, 50% glycerol

Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.

Microsome membrane, Peripheral membrane protein, Endoplasmic reticulum membrane, Peripheral membrane protein

VEGFsignalingpathway