Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Menge |
200ug |
Host |
E.coli |
ArtNr |
CSB-RP015154h-200 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Transport |
Uniprot ID |
P08574 |
Gene Names |
CYC1 |
Organism |
Homo sapiens (Human) |
AA Sequence |
SDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQ VCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEV QDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAAN NGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTG VSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGT PATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLM MMALLVPLVYTIKRHKWSVLKSRKLAYRPPK |
Expression Region |
85-325aa |
Sequence Info |
Full Length of Mature Protein |
Source |
E.coli |
Tag Info |
N-terminal GST-tagged |
MW |
54.4 kDa |
Alternative Name(s) |
Complex III subunit 4Complex III subunit IVCytochrome b-c1 complex subunit 4Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit ; Cytochrome c-1 |
Relevance |
This is the he-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. |
Reference |
Nucleotide sequence of a cDNA encoding the precursor to human cytochrome c1.Nishikimi M., Ohta S., Suzuki H., Tanaka T., Kikkawa F., Tanaka M., Kagawa Y., Ozawa T.Nucleic Acids Res. 16:3577-3577(1988) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain. |
Involvement in disease |
Mitochondrial complex III deficiency, nuclear 6 (MC3DN6) |
Subcellular Location |
Mitochondrion inner membrane, Single-pass membrane protein, Intermembrane side |
Protein Families |
Cytochrome c family |
Paythway |
Cardiacmusclecontraction |
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