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Recombinant Human 14-3-3 protein eta(YWHAH),partial

Recombinant Human 14-3-3 protein eta(YWHAH),partial

Hersteller	Cusabio
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Human
Format	Liquid or Lyophilized powder
Menge	1mg
Host	E.coli
ArtNr	CSB-RP021744h-1
Konjugat/Tag	GST
eClass 6.1	34160400
eClass 9.0	42020190
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Research Areas	Signal Transduction
Target / Protein	YWHAH
Biologically Active	Not Test
Expression System	E.coli
Species of origin	Homo sapiens (Human)
Uniprot ID	Q04917
AA Sequence	REQLLQRARLAEQAERYDDMASAMKAVTELNEPLS NEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMAD GNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFL IKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKK NSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALN FSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNE DSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN
Tag Info	N-terminal GST-tagged
Expression Region	4-246aa
Protein Length	Partial
MW	54.9 kDa
Distributor Discount	50% off the list price
Alternative Name(s)	Protein AS1
Relevance	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Reference	A genome annotation-driven approach to cloning the human ORFeome.Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I.Genome Biol. 5:R84.1-R84.11(2004)
Purity	Greater than 90% as determined by SDS-PAGE.
Form	Liquid or Lyophilized powder
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Protein Families	14-3-3 family
Tissue Specificity	Expressed mainly in the brain and present in other tissues albeit at lower levels.
Paythway	Hipposignalingpathway
Tag Information	N-terminal GST-tagged

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