Subcellular Location |
Isoform 1: Cell membrane, Single-pass type I membrane protein, Lateral cell membrane, Apical cell membrane, Basal cell membrane, Cell junction, Cell junction, adherens junction, Note=Canalicular domain of hepatocyte plasma membranes, Found as a mixture of monomer, dimer and oligomer in the plasma membrane, Occurs predominantly as cis-dimers and/or small cis-oligomers in the cell junction regions, Found as dimer in the solution, Predominantly localized to the lateral cell membranes, SUBCELLULAR LOCATION: Isoform 2: Secreted, SUBCELLULAR LOCATION: Isoform 3: Secreted, SUBCELLULAR LOCATION: Isoform 4: Secreted, SUBCELLULAR LOCATION: Isoform 5: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 6: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 7: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 8: Cell membrane, Single-pass type I membrane protein, Cytoplasmic vesicle, secretory vesicle membrane, Lateral cell membrane, Apical cell membrane, Basal cell membrane, Cell junction, Cell junction, adherens junction, Note=Predominantly localized to the lateral cell membranes, Found as a mixture of monomer, dimer and oligomer in the plasma membrane, Occurs predominantly as cis-dimers and/or small cis-oligomers in the cell junction regions (By similarity), Co-localizes with ANXA2 in secretory vesicles and with S100A10/p11 at the plasma membrane (PubMed:14522961), SUBCELLULAR LOCATION: Cell projection, microvillus membrane, Single-pass type I membrane protein, Apical cell membrane, Single-pass type I membrane protein |