Recombinant Human Heterogeneous nuclear ribonucleoprotein M(HNRNPM)

Epigenetics and Nuclear Signaling

Not Test

Homo sapiens (Human)

AAGVEAAAEVAATEIKMEEESGAPGVPSGNGAPGP KGEGERPAQNEKRKEKNIKRGGNRFEPYANPTKRY RAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMD AEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRP LKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGM ITIPPSILNNPNIPNEIIHALQAGRLGSTVFVANL DYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGI GTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDER ALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPID ANHLNKGIGMGNIGPAGMGMEGIGFGINKMGGMEG PFGGGMENMGRFGSGMNMGRINEILSNALKRGEII AKQGGGGGGGSVPGIERMGPGIDRLGGAGMERMGA GLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIER MGPLGLDHMASSIERMGQTMERIGSGVERMGAGMG FGLERMAAPIDRVGQTIERMGSGVERMGPAIERMG LSMERMVPAGMGAGLERMGPVMDRMATGLERMGAN NLERMGLERMGANSLERMGLERMGANSLERMGPAM GPALGAGIERMGLAMGGGGGASFDRAIEMERGNFG GSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTW KMLKDKFNECGHVLYADIKMENGKSKGCGVVKFES PEVAERACRMMNGMKLSGREIDVRIDRNA

2-730aa

93.4 kDa

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012)

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.

Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

N-terminal 6xHis-SUMO-tagged