Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
500ug |
Host |
E.coli |
ArtNr |
CSB-EP011670MO-500 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Immunology |
Uniprot ID |
P16872 |
Gene Names |
Il7r |
Organism |
Mus musculus (Mouse) |
AA Sequence |
ESGNAQDGDLEDADADDHSFWCHSQLEVDGSQHLL TCAFNDSDINTANLEFQICGALLRVKCLTLNKLQD IYFIKTSEFLLIGSSNICVKLGQKNLTCKNMAINT IVKAEAPSDLKVVYRKEANDFLVTFNAPHLKKKYL KKVKHDVAYRPARGESNWTHVSLFHTRTTIPQRKL RPKAMYEIKVRSIPHNDYFKGFWSEWSPSSTFETP EPKNQGGWD |
Expression Region |
21-239aa |
Sequence Info |
Extracellular Domain |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
MW |
41 kDa |
Alternative Name(s) |
Short name: IL-7 receptor subunit alpha Short name: IL-7R subunit alpha Short name: IL-7R-alpha Short name: IL-7RA |
Relevance |
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Reference |
"Structural basis of the proinflammatory signaling complex mediated by TSLP."Verstraete K., van Schie L., Vyncke L., Bloch Y., Tavernier J., Pauwels E., Peelman F., Savvides S.N.Nat. Struct. Mol. Biol. 21:375-382(2014) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Subcellular Location |
Membrane, Single-pass type I membrane protein |
Protein Families |
Type I cytokine receptor family, Type 4 subfamily |
Tissue Specificity |
Spleen, thymus and fetal liver. |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
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