Vergleich

Recombinant Human Neurofilament light polypeptide(NEFL)

Hersteller Cusabio
Kategorie
Typ Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Menge 500ug
Host E.coli
ArtNr CSB-EP015688HU-500
Konjugat/Tag Myc
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Research areas
others
Target / Protein
NEFL
Biologically active
Not Test
Expression system
E.coli
Species of origin
Homo sapiens (Human)
Uniprot ID
P07196
AA Sequence
SSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTA RSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENL DLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIE RVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQ EIRDLRLAAEDATNEKQALQGEREGLEETLRNLQA RYEEEVLSREDAEGRLMEARKGADEAALARAELEK RIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVE MDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFK SRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKT LEIEACRGMNEALEKQLQELEDKQNADISAMQDTI NKLENELRTTKSEMARYLKEYQDLLNVKMALDIEI AAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGR SAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEE TIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEA AEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEE EKKVEGAGEEQAAKKKD
Tag Info
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Expression Region
2-543aa
Protein length
Full Length of Mature Protein
MW
81.4 kDa
Alternative Name(s)
68 kDa neurofilament protein
Neurofilament triplet L protein
Relevance
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
References
"The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family."Julien J.-P., Grosveld F., Yazdanbaksh K., Flavell D., Meijer D., Mushynski W.Biochim. Biophys. Acta 909:10-20(1987)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Neurofilaments usually contain three intermediate filament proteins
Involvement in disease
Charcot-Marie-Tooth disease 1F (CMT1F); Charcot-Marie-Tooth disease 2E (CMT2E)
Protein Families
Intermediate filament family
Tag Information
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500ug
Lieferbar: In stock
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