Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
10ug |
Host |
E.coli |
ArtNr |
CSB-EP019519HU-10 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research areas |
Neuroscience |
Target / Protein |
RCVRN |
Biologically active |
Not Test |
Expression system |
E.coli |
Species of origin |
Homo sapiens (Human) |
Uniprot ID |
P35243 |
AA Sequence |
GNSKSGALSKEILEELQLNTKFSEEELCSWYQSFL KDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFR SFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAF SLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLL PDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGT LANKEILRLIQFEPQKVKEKMKNA |
Tag Info |
N-terminal 6xHis-tagged |
Expression Region |
2-200aa |
Protein length |
Full Length of Mature Protein |
MW |
27.0 kDa |
Alternative Name(s) |
Cancer-associated retinopathy protein ; Protein CAR |
Relevance |
Ses to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. |
References |
Expression of a photoreceptor protein, recoverin, as a cancer-associated retinopathy autoantigen in human lung cancer cell lines.Matsubara S., Yamaji Y., Sato M., Fujita J., Takahara J.Br. J. Cancer 74:1419-1422(1996) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse. |
Protein Families |
Recoverin family |
Tissue Specificity |
Retina and pineal gland. |
Tag Information |
N-terminal 6xHis-tagged |
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