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Recombinant Rat Regenerating islet-derived protein 3-alpha(Reg3a)

Hersteller Cusabio
Kategorie
Typ Proteins Recombinant
Specific against other
Format Liquid or Lyophilized powder
Menge 100ug
Host E.coli
ArtNr CSB-EP019548RA-100
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Research areas
Others
Target / Protein
Reg3a
Biologically active
Not Test
Expression system
E.coli
Species of origin
Rattus norvegicus (Rat)
Uniprot ID
P35231
AA Sequence
EDSQKAVPSTRTSCPMGSKAYRSYCYTLVTTLKSW FQADLACQKRPSGHLVSILSGGEASFVSSLVTGRV NNNQDIWIWLHDPTMGQQPNGGGWEWSNSDVLNYL NWDGDPSSTVNRGNCGSLTATSEFLKWGDHHCDVE LPFVCKFKQ
Tag Info
N-terminal 6xHis-tagged
Expression Region
26-174aa
Protein length
Full Length of Mature Protein
MW
20.5 kDa
Alternative Name(s)
Islet of Langerhans regenerating protein 3 ; REG 3Lithostathine 3; Pancreatitis-associated protein 2RegIIIRegenerating islet-derived protein III-alpha ; Reg III-alpha
Relevance
Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway .
References
Identification of a second rat pancreatitis-associated protein. Messenger RNA cloning, gene structure, and expression during acute pancreatitis.Frigerio J.-M., Dusetti N.J., Keim V., Dagorn J.-C., Iovanna J.L.Biochemistry 32:9236-9241(1993)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway (By similarity).
Involvement in disease
Overexpressed during the acute phase of pancreatitis.
Subcellular Location
Secreted
Tissue Specificity
Low expression found in healthy pancreas.
Tag Information
N-terminal 6xHis-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ug
Lieferbar: In stock
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