Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
500ug |
Host |
E.coli |
ArtNr |
CSB-EP316614DAE-500 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research areas |
others |
Biologically active |
Not Test |
Expression system |
E.coli |
Species of origin |
Dahlia merckii (Bedding dahlia) |
Uniprot ID |
P0C8Y4 |
AA Sequence |
ELCEKASKTWSGNCGNTGHCDNQCKSWEGAAHGAC HVRNGKHMCFCYFNC |
Tag Info |
N-terminal 6xHis-B2M-tagged |
Expression Region |
1-50aa |
Protein length |
Full Length |
MW |
19.5 kDa |
Alternative Name(s) |
Cysteine-rich antimicrobial protein 1 Defensin AMP1 |
Relevance |
Possesses antimicrobial activity sensitive to inorganic cations. Has no inhibitory effect on insect gut alpha-amylase. Induces potential changes in fungal membranes and increased K+ efflux and Ca2+ uptake. Interacts with sphingolipids and ergosterols found in fungal plasma membranes. |
References |
"Fungal membrane responses induced by plant defensins and thionins." Thevissen K., Ghazi A., De Samblanx G.W., Brownlee C., Osborn R.W., Broekaert W.F. J. Biol. Chem. 271:15018-15025(1996) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Possesses antimicrobial activity sensitive to inorganic cations. Has no inhibitory effect on insect gut alpha-amylase. Induces potential changes in fungal membranes and increased K+ efflux and Ca(2+) uptake. Interacts with sphingolipids and ergosterols found in fungal plasma membranes. |
Subcellular Location |
Secreted |
Protein Families |
DEFL family |
Tag Information |
N-terminal 6xHis-B2M-tagged |
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