Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
500ug |
Host |
Yeast |
ArtNr |
CSB-YP001566HU-500 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research areas |
Neuroscience |
Target / Protein |
ALDH1A2 |
Biologically active |
Not Test |
Expression system |
Yeast |
Species of origin |
Homo sapiens (Human) |
Uniprot ID |
O94788 |
AA Sequence |
MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEI KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQ EADKADIDKAVQAARLAFSLGSVWRRMDASERGRL LDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHE PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPT AGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL KRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFN QGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN KALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSG NGREMGEFGLREYSEVKTVTVKIPQKNS |
Tag Info |
N-terminal 6xHis-tagged |
Expression Region |
1-518aa |
Protein length |
Full Length |
MW |
58.7 kDa |
Alternative Name(s) |
Aldehyde dehydrogenase family 1 member A2 Retinaldehyde-specific dehydrogenase type 2 Short name: RALDH(II) |
Relevance |
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently |
References |
"TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3."Ono Y., Fukuhara N., Yoshie O.Mol. Cell. Biol. 18:6939-6950(1998) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity). |
Subcellular Location |
Cytoplasm |
Protein Families |
Aldehyde dehydrogenase family |
Tag Information |
N-terminal 6xHis-tagged |
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