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Human CXCR5 Protein-Nanodisc (CXR5-HM1N72)

Human CXCR5 Protein-Nanodisc (CXR5-HM1N72)

ArtNr	CXR5-HM1N72-100UG
Hersteller	KactusBio
Menge	100 ug
Kategorie	Neuroscience Neuroinflammatio
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	HIS
Dry ice	Yes
Sequence	Met1-Phe372
Alias	CXC-R5,CXCR-5,MDR-15,MDR15,CD185,BLR1
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	CXCR5
Manufacturer - Conjugate / Tag	C-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 43.3 kDa.
Description	Recombinant Human CXCR5 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus (FITC-equivalent protein is fused on cytoplasmic part).It contains Met1-Phe372.
Background	CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CXR5-HM1N72-100UG-datasheet.pdf

CXR5-HM1N72-100UG-safety-datasheet.pdf