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Rat IL-1beta ELISA Kit

ArtNr OCE-EK301B
Hersteller Bio-Ocean
Menge 96T
Kategorie
Typ Elisa-Kit
Applikationen ELISA
Specific against Rat (Rattus norvegicus)
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Lieferbar
Leadtime
2 -3 days
Shipping
Blue ice
Antigen
IL-1beta
Detection range
1.42 - 2000 pg/ml
Detection minimum
1.42 pg/ml
Protocol
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IL-1beta. The Rat IL-1beta ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin 1 (IL-1) is an extracellular peptide of 17 kDa that designates two proteins, IL-1alpha and IL-1beta. IL-1beta is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.The interleukin-1 (IL-1) species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses. Increased production of IL-1beta causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as CAPS, due to mutations in the inflammasome receptor NLRP3 which triggers processing of IL-1beta.
Components
plate, standard, diluent
Methode type
Sandwich
Detection Method
Colorimetric
Principle
ELISA detection, IL-1beta, Sandwich ELISA assay
Plate
solid
Storage
4CC
Sample type
serum, plasma, cell culture supernates
Sample volume
100uL
Assay time
3-4h
Specificity
Rat IL-1beta ELISA Kit
Assay precision
Three samples were tested on one plate
Preservative
0.02% sodium azide
Precaution
protect your eyes
Not included
pipettes, tubes, reader
Description
Interleukin 1 (IL-1) is an extracellular peptide of 17 kDa that designates two proteins, IL-1alpha and IL-1beta. IL-1beta is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.The interleukin-1 (IL-1) species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses.
Gene ID
NM_031512
Swiss-Prot
Q63264
Molecular Weight
Online product mannual
Assay procedure
Online product mannual
Reagent preparation
Online product mannual
Results calculation
Online product mannual
Sample collection
Online product mannual
Sample preparation
Online product mannual
Related products
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 96T
Lieferbar: In stock
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