TNFSF10/TRAIL/APO-2L

ArtNr	E21-022
Hersteller	Enogene
Menge	10 ug
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Cardiovascular Research Ischemia & Reperfusion Injury
Typ	Proteins
Format	Lyophilized
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	Greater than 95% as determined by reducing SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Tumor Necrosis Factor Ligand Superfamily Member 10,Apo-2 Ligand,Apo-2L,TNF-Related Apoptosis-Inducing Ligand,Protein TRAIL,CD253,TNFSF10,APO2L,TRAIL
Versandbedingung	Raumtemperatur
Lieferbar
Shipping Temperature	The product is shipped at ambient temperature. Ambient
Storage Conditions	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Background	Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
Description	Recombinant Human TNF-Related Apoptosis-Inducing Ligand is produced by our E.coli expression system and the target gene encoding Arg115-Gly281 is expressed.
Endotoxin	Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Formulation Description	Lyophilized from a 0.2 μm filtered solution of 150mM NaCl.
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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E21-022-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 23.10.2025

Express-Lieferung: 24 Tage sparen

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