CXCR2 Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-CXCR2 Polyclonal Antibody detects human CXCR2 protein. It has not yet been tested for other species.

CXCR2 is a member of the GPCR family (subfamily, chemokine). It is a receptor for Interleukin 8 (IL8), which is a powerful neutrophil chemotactic factor. Binding of IL8 with the receptor activates neutrophils. This response is mediated by a second messenger system in which G-protein activates phosphatidyl inositol-calcium. This receptor binds to IL8, GRO/MGSA, and NAP2 with a high affinity. Its expression has been reported to be in a wide variety of tissues. GenScript, Rabbit Anti-CXCR2 Polyclonal Antibody, is developed in rabbit using a KLH-coupled synthetic peptide derived from N-terminal extracellular domain of human CXCR2.

Immunoaffinity chromatography

Small volume of antibody will occasionally become entrapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.