Caspase 10 Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-Caspase 10 Polyclonal Antibody detects human caspase 10 protein.

Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and is responsible for the execution of apoptosis. Caspase 10 is recruited to both Fas- and TNFR-1 receptors in a FADD-dependent manner. Caspase 10 may participate in the granzyme B apoptotic pathways. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) having the same prodomain but different mature large and small subdomains have been described to date. GenScript, Rabbit Anti-Caspase 10 Polyclonal Antibody, is developed in rabbit hosts using a KLH-coupled synthetic peptide residues 280-330 of human caspase 10 protein (Swiss Prot: Q92851).

Immunoaffinity chromatography

60 kD

Small volumes of antibody will occasionally become trapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.