Prohibitin Antibody, pAb, Rabbit

USA

GenScript Rabbit Anti-Prohibitin Polyclonal Antibody detects endogenous levels of human, mouse, and rat prohibitin protein.

Prohibitin is located in the inner membrane of the mitochondria. It is expressed in a variety of tissues. Prohibitin inhibits DNA synthesis and plays a role in regulating negative cell proliferation. It may also be a tumor suppressor. Mutations in prohibitin have been linked to sporadic breast cancer. However, it is not yet clear whether it is the protein itself or the associated mRNA that exhibits these effects. Prohibitin may also play a role in regulating mitochondrial respiration activity and in aging. GenScript, Rabbit Anti-Prohibitin Polyclonal Antibody, is developed in rabbit hosts using a KLH-coupled synthetic peptide within residues 100-150 of human prohibitin protein (Swiss Prot: P35232).

Immunoaffinity chromatography

30 kD

Small volumes of antibody will occasionally become trapped in the seal of the product vial during shipment and storage. Before use, briefly centrifuge the vial to dislodge any liquid in the container's cap.