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Epithelial Membrane Protein (EMP)-1

Epithelial Membrane Protein (EMP)-1

ArtNr	RP13257
Hersteller	GenScript
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Signaling Peptides & Proteins Peptides By Organ Lung Cancer Bladder Cancer
Typ	Peptides
Specific against	other
Purity	> 95%
Sequence	GGTYSCHFGPLTWVCKPQGG ; {GLY}{GLY}{THR}{TYR}{SER}{CYS}{HIS}{PHE}{GLY}{PRO}{LEU}{THR}{TRP}{VAL}{CYS}{LYS}{PRO}{GLN}{GLY}{GLY}
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	peptide/RP13257-Epithelial_membrane_protein-1_EMP-1, EMP-1 is identified as a surface biomarker whose expression correlates with acquisition of gefitinib resistance. EMP-1 expression is further correlated with lack of complete or partial response to gefitinib in lung cancer patient samples as well as clinical progression to secondary gefitinib resistance. EMP-1 expression and acquisition of gefitinib clinical resistance is independent of gefitinib-sensitizing EGFR somatic mutations. </td></tr><tr><th>Solubility</th><td colspan="7"> Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. </td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Before using, store the peptide in the DRY form at 0 - 5C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. </td></tr>
Similar products	Epithelial
Lieferbar
Country of Origin	USA
Storage Conditions	Before using, store the peptide in the DRY form at 0 - 5C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
Description	EMP-1 is identified as a surface biomarker whose expression correlates with acquisition of gefitinib resistance. EMP-1 expression is further correlated with lack of complete or partial response to gefitinib in lung cancer patient samples as well as clinical progression to secondary gefitinib resistance. EMP-1 expression and acquisition of gefitinib clinical resistance is independent of gefitinib-sensitizing EGFR somatic mutations.
Solubility	Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Chemical Bridge	Disulfide bond: Cys6-Cys15

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Menge: 0.1 mg

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