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Atriopeptin I, rat Europäischer Partner

ArtNr RP11201-0.5
Hersteller GenScript
Menge 0.5mg
Kategorie
Typ Peptides
Specific against Rat
Purity > 95%
Sequence SSCFGGRIDRIGAQSGLGCNS ; {SER}{SER}{CYS}{PHE}{GLY}{GLY}{ARG}{ILE}{ASP}{ARG}{ILE}{GLY}{ALA}{GLN}{SER}{GLY}{LEU}{GLY}{CYS}{ASN}{SER}
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias peptide/RP11201-Atriopeptin_I_rat, Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. Elevated plasma atriopeptin levels may be produced in experimental models by volume expansion, high salt diets, and in response to vasoconstrictors. Increased plasma concentrations have also been reported in various pathological conditions such as renal disease, congestive heart failure, and paroxysmal atrial tachycardia.</td></tr><tr><th>Purity</th><td colspan="7"> > 95% </td></tr><tr><th>Storage</th><td colspan="7"> Store at -20C </td></tr>
Similar products Atriopeptin
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Chemical Bridge
Disulfide bridge: Cys3-Cys19
Description
Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. Atriopeptin acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium due to blood volume overload. Atriopeptin then acts at the nephron to increase salt and water excretion, lowering blood volume and blood pressure. Elevated plasma atriopeptin levels may be produced in experimental models by volume expansion, high salt diets, and in response to vasoconstrictors. Increased plasma concentrations have also been reported in various pathological conditions such as renal disease, congestive heart failure, and paroxysmal atrial tachycardia.
Storage
Store at -20C
Product Origin
USA

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Menge: 0.5mg
Lieferbar: In stock
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