GOAT ANTI HUMAN IgG (H/L)

GWB-F42D21

Polyclonal IgG

Recognizes human IgG. This reagent is available in bulk quantities and may be made available in other formats. Please enquire for further details. Recommended Secondary Antibodies: Rabbit Anti Goat IgG (Fc)

Nie has the G1M(17) allotypic marker 97-K and the G1M1 markers 239-D and 241-L. KOL and EU sequences have the G1M3 marker and the G1M (non-1) markers. Nie also differs in the amidation states of 35 116 198 269 and 272. EU also differs in the amidation states of residues 155 166 177 195 198 269 and 272 and in the order of residues 268-272. KOL also differs in the amidation states of residues 198 267 and 272. Sequence cautionThe sequence AAC82527. 1 differs from that shown. Reason: Erroneous initiation. 1. Kadowaki N. et al. (2000) Natural interferon alpha/beta-producing cells link innate and adaptive immunity. J. Exp. Med. 192: 219-225. 2. Butler D. et al. (1997) DBA/1 mice expressing the human TNF-alpha transgene develop a severe erosive arthritis: characterization of the cytokine cascade and cellular composition. J. Immunol. 159: 2867-2876. 3. Abrams J. (1995) Immunoenzymatic assay of mouse and human cytokines using NIP-labelled anti-cytokine antibodies. Current Protocols in Immunology. Edited by Coligan J. et al. John Wiley and Sons. 4. Evans H. G. et al. (2009) In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc Natl Acad Sci U S A. 106: 6232-7. 5. Vujanovic L. et al. (2010) Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15. Blood. 116: 575-83. [1] \" Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome. \" Nedospasov S. A. Shakhov A. N. Turetskaya R. L. Mett V. A. Azizov M. M. Georgiev G. P. Korobko V. G. Dobrynin V. N. Filippov S. A. Bystrov N. S. Boldyreva E. F. Chuvpilo S. A. Chumakov A. M. Shingarova L. N. Ovchinnikov Y. A. Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986) [PubMed: 3555974] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [2] \" Human tumour necrosis factor: precursor structure expression and homology to lymphotoxin. \" Pennica D. Nedwin G. E. Hayflick J. S. Seeburg P. H. Derynck R. Palladino M. A. Kohr W. J. Aggarwal B. B. Goeddel D. V. Nature 312:724-729(1984) [PubMed: 6392892] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [3] \" Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. \" Shirai T. Yamaguchi H. Ito H. Todd C. W. Wallace R. B. Nature 313:803-806(1985) [PubMed: 3883195] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [4] \" Human lymphotoxin and tumor necrosis factor genes: structure homology and chromosomal localization. \" Nedwin G. E. Naylor S. L. Sakaguchi A. Y. Smith D. H. Jarrett-Nedwin J. Pennica D. Goeddel D. V. Gray P. W. Nucleic Acids Res. 13:6361-6373(1985) [PubMed: 2995927] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. [5] \" Molecular cloning of the complementary DNA for human tumor necrosis factor. \" Wang A. M. Creasey A. A. Ladner M. B. Lin L. S. Strickler J. van Arsdell J. N. Yamamoto R. Mark D. F. Science 228:149-154(1985) [PubMed: 3856324] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA]. [6] \" Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor. \" Marmenout A. Fransen L. Tavernier J. van der Heyden J. Tizard R. Kawashima E. Shaw A. Johnson M. J. Semon D. Mueller R. Ruysschaert M. -R. van Vliet A. Fiers W. Eur. J. Biochem. 152:515-522(1985) [PubMed: 3932069] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [7] \" Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. \" Iris F. J. M. Bougueleret L. Prieur S. Caterina D. Primas G. Perrot V. Jurka J. Rodriguez-Tome P. Claverie J. -M. Dausset J. Cohen D. Nat. Genet. 3:137-145(1993) [PubMed: 8499947] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [8] \" A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. \" Neville M. J. Campbell R. D. J. Immunol. 162:4745-4754(1999) [PubMed: 10202016] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. [9] \" Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. \" Xie T. Rowen L. Aguado B. Ahearn M. E. Madan A. Qin S. Campbell R. D. Hood L. Genome Res. 13:2621-2636(2003) [PubMed: 14656967] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. [10] \" Homo sapiens 2 229 817bp genomic DNA of 6p21. 3 HLA class I region. \" Shiina S. Tamiya G. Oka A. Inoko H. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].