MOUSE ANTI HUMAN TdT:FITC

TdT

Phosphate buffered saline

OBT0012 is a mixture of 4 monoclonal antibodies specific for human terminal deoxynucleotidyl transferase (TdT). TdT is a DNA polymerase responsible for the catalysis of non-reversible addition of deoxynucleotides to the 3\' end hydroxy groups of DNA. TdT levels are enhanced in all forms of acute lymphoblastic leukaemia (ALL) and in a significant number of chronic lymphoblastic leukaemia cases (CML). TdT is not expressed in the majority of myeloid leukaemias non-Hodgkins lymphomas or mature lymphoid leukaemias. 1. Grisar J. et al. (2001) Phenotypic characteristics of human monocytes undergoing transendothelial migration. Arthritis. Res. 3: 127 - 132.