RAT ANTI MOUSE CD4:RPE

GWB-39E7AC

IgG2a

Phosphate buffered saline pH7. 2

BALB/c mouse thymocytes

Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Subunit structureAssociates with p56-LCK. Interacts with SPG21 By similarity. Subcellular locationMembrane; Single-pass type I membrane protein. Sequence similaritiesContains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. [1] \" A mammalian telomerase-associated protein. \" Harrington L. McPhail T. Mar V. Zhou W. Oulton R. Bass M. B. Arruda I. Robinson M. O. Science 275:973-977(1997) [PubMed: 9020079] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) TISSUE SPECIFICITY VARIANTS PRO-116; GLY-553; CYS-1055; GLN-1155 AND PRO-1195. [2] \" The status quality and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). \" The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Cerebellum. [3] \" The full-ORF clone resource of the German cDNA consortium. \" Bechtel S. Rosenfelder H. Duda A. Schmidt C. P. Ernst U. Wellenreuther R. Mehrle A. Schuster C. Bahr A. Bloecker H. Heubner D. Hoerlein A. Michel G. Wedler H. Koehrer K. Ottenwaelder B. Poustka A. Wiemann S. Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2288-2627 (ISOFORM 2). Tissue: Salivary gland. [4] \" Human telomerase contains evolutionarily conserved catalytic and structural subunits. \" Harrington L. Zhou W. McPhail T. Oulton R. Yeung D. S. Mar V. Bass M. B. Robinson M. O. Genes Dev. 11:3109-3115(1997) [PubMed: 9389643] [Abstract]Cited for: IDENTIFICATION IN THE TELOMERASE RIBONUCLEOPROTEIN COMPLEX. [5] \" Vaults and telomerase share a common subunit TEP1. \" Kickhoefer V. A. Stephen A. G. Harrington L. Robinson M. O. Rome L. H. J. Biol. Chem. 274:32712-32717(1999) [PubMed: 10551828] [Abstract]Cited for: IDENTIFICATION IN THE VAULTS RIBONUCLEOPROTEIN PARTICLE RNA-BINDING. [6] \" Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding. \" Beattie T. L. Zhou W. Robinson M. O. Harrington L. Mol. Biol. Cell 11:3329-3340(2000) [PubMed: 11029039] [Abstract]Cited for: IDENTIFICATION IN THE TELOMERASE RIBONUCLEOPROTEIN COMPLEX. [7] \" A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. \" Venteicher A. S. Abreu E. B. Meng Z. McCann K. E. Terns R. M. Veenstra T. D. Terns M. P. Artandi S. E. Science 323:644-648(2009) [PubMed: 19179534] [Abstract]Cited for: IDENTIFICATION IN THE TELOMERASE HOLOENZYME COMPLEX.