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Fluorescein Conjugated Affinity Purified Anti-MOUSE IgA (alpha chain) (RABBIT)

ArtNr 25-732-294319
Hersteller GENWAY
Menge 1 mg
Kategorie
Typ Antibody
Applikationen WB, IHC, ELISA
Specific against Mouse (Murine, Mus musculus)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GWB-A8D92D
Similar products 25-732-294319
Lieferbar
Genway ID:
GWB-A8D92D
Antigen:
IgA or Alpha Heavy Chain
Immunogen:
Mouse IgA ? alpha chainF/P Ratio: 8. 3 moles FITC per mole of Rabbit IgGConjugation Reference: Modified from The and Feltkamp immunology 18; 865 1970. Conjugation Chemistry: IsothiocyanateExcitation Wavelength: 495Emission Wavelength: 528 Family: Affinity PurifiedFraction: Affinity Purified IgGPurity
Note:
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Fluorescein anti-Rabbit Serum Mouse IgG Mouse IgG F(ab?)2 and Mouse Serum. No reaction was observed against Mouse IgG F(c).
Conjugation:
FluoresceinApplication: Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring lot-to-lot consistency Antibody
Concentration:
Lot specific and is stated on the vialLabel: Fluorescein isothiocyanate (FITC) (Molecular Weight 390 daltons)
Buffer:
0. 02 M Potassium Phosphate 0. 15 M Sodium Chloride pH 7. 2
Stabilizer:
10 mg/ml Bovine Serum Albumin (BSA) IgG and Protease free
Function:
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:
Monomeric or polymeric.
Ptm:
3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:
A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:
Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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