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Peroxidase Conjugated Affinity Purified Anti-MOUSE IgA (alpha chain) (RABBIT)

Peroxidase Conjugated Affinity Purified Anti-MOUSE IgA (alpha chain) (RABBIT)

ArtNr	25-732-294333
Hersteller	GENWAY
Menge	1 mg
Kategorie	Oncology Antibodies By Cell Type Hematology Lymphoma Cell Biology Cell Metabolism Immunohistochemistry Western Blot ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Typ	Antibody
Applikationen	WB, IHC, ELISA
Specific against	Mouse (Murine, Mus musculus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-885624
Similar products	25-732-294333
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Genway ID:	GWB-885624
Antigen:	IgA or Alpha Heavy Chain
Immunogen:	Mouse IgA heavy chain
Preservative:	0. 01% (w/v) ThimerisolApplication(s): Suitable for immunoblotting (western or dot blot) ELISA immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency. Family: Affinity PurifiedFraction: Affinity Purified IgG
Conjugation:	PeroxidaseConjugation Reference: Farr & Nakane J. Immunol. Methods 47; 129-144. 1981.
Application:	Suitable for immunoblotting (western or dot blot) ELISA immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency. Recommended
Dilution:	This product has been assayed against 1. 0 mg of Mouse IgA in a standard capture ELISA using ABTS (2 2\' -azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) as a substrate for 30 minutes at room temperature. A working dilution of 1:2 000 to 1:10 000 of the reconstitution concentration is suggested for this product. Optimal titers for other applications should be determined by the researcher. ELISA: 1:100 000WB: 1:2 000-1:10 000IHC: 1:1000-1:5 000Physical State: LyophilizedPurity and
Specificity:	This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgA coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase anti-Rabbit Serum Mouse IgA and Mouse Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other mouse heavy and light chain isotypes. Antibody
Concentration:	Lot specific and is stated on the vial. Label: Horseradish Peroxidase (HRP)
Buffer:	0. 02 M Potassium Phosphate 0. 15 M Sodium Chloride pH 7. 2
Stabilizer:	10 mg/ml Bovine Serum Albumin (BSA) IgG and Protease free
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 mg

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