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Biotin Conjugated Affinity Purified anti-Mouse IgA ? (alpha chain specific) [Rabbit]

Biotin Conjugated Affinity Purified anti-Mouse IgA ? (alpha chain specific) [Rabbit]

ArtNr	25-732-294361
Hersteller	GENWAY
Menge	1 mg
Kategorie	Oncology Antibodies By Cell Type Hematology Lymphoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Secondary Antibodies By Organ Lymphatic System Cancer
Typ	Antibody
Applikationen	WB, IP, IHC, ELISA
Specific against	Mouse (Murine, Mus musculus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-A0B8F5
Similar products	25-732-294361
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Genway ID:	GWB-A0B8F5
Antigen:	IgA or Alpha Heavy Chain
Immunogen:	Mouse IgA ? chain Family: Affinity PurifiedFraction: Affinity Purified IgG
Conjugation:	BiotinConjugation Reference: Bayer & Wilchek Methods in Enzymology 184; 138-160 1990.
Application:	immunoblotting ELISA immunohistochemistry immunomicroscopy as well as other antibody based assays using streptavidin or avidin conjugates requiring lot-to-lot consistency. Physical State: Lyophilized
Preservative:	0. 01% (w/v) Sodium AzidePurity and
Specificity:	This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse IgA coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arcagainst anti-biotin anti-Rabbit Serum Mouse IgA and Mouse Serum. No reaction was observed against other Mouse heavy or light chain proteins. Antibody
Concentration:	1. 0 mg/ml (by UV absorbance at 280 nm)Label: Biotinamidocaproate N-Hydroxysuccinimide Ester (BAC)
Buffer:	0. 02 M Potassium Phosphate 0. 15 M Sodium Chloride pH 7. 2
Stabilizer:	10 mg/ml Bovine Serum Albumin (BSA) IgG and Protease free
Function:	Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
Subunit:	Monomeric or polymeric.
Ptm:	3-Hydroxykynurenine an oxidized tryptophan metabolite that is common in biological fluids reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.
Disease:	A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1; 14)(q21; q32) that forms a FCRL4-IGHA1 fusion protein.
Similarity:	Contains 3 Ig-like (immunoglobulin-like) domains.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 mg

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