CACNB3 (calcium channel. voltage-dependent. beta 3 subunit)

Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human CACNB3. Western Blot: Suggested dilution at 2. 5 microg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50. 000 - 100. 000 as second antibody.

Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. The L-type calcium channel is composed of four subunits: alpha-1 alpha-2 beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current shifting the voltage dependencies of activation and inactivation modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

The L-type calcium channel is composed of four subunits: alpha-1 alpha-2 beta and gamma. Interacts with CACNA2D4.

Belongs to the calcium channel beta subunit family.