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SARS (seryl-tRNA synthetase)

SARS (seryl-tRNA synthetase)

ArtNr	18-003-44206
Hersteller	GENWAY
Menge	0.1 mg
Kategorie	Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies Western Blot Primary Antibodies
Typ	Antibody
Applikationen	WB
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-46EA63
Similar products	18-003-44206
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Genway ID:	GWB-46EA63
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human SARS.
ELISA Titre:	1:62500
Category:	RNA Binding Proteins
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. SARS belongs to the class II amino-acyl tRNA family. The enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the
Function:	Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine to form the misacylated tRNA L-seryl-tRNA(Sec) which will be further converted into selenocysteinyl-tRNA(Sec).
Catalytic Activity:	ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
Catalytic Activity:	ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
Pathway:	Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
Subunit:	Homodimer. The tRNA molecule binds across the dimer (By similarity).
Subcellular Location:	Cytoplasm.
Domain:	Consists of two distinct domains a catalytic core and a N-terminal extension that is involved in tRNA binding (By similarity).
Ptm:	Phosphorylated upon DNA damage probably by ATM or ATR.
Similarity:	Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily [view classification]. Summary: This protein belongs to the class II amino-acyl tRNA family The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Shimada. N. . (2001) J. Biol. Chem. 276 (50). 46770-46778.

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Menge: 0.1 mg

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Lieferung vsl. bis 11.09.2025

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