Toxoplasma gondii (FITC )

IgG

Purified trophozoites - Crossreactivity to tachyzoites has not been tested.

Whole cell

4 - 5 mg/ml

0. 01M PBS 10mg/ml BSA pH 7. 2 with 0. 1% aodium azide as a preservative

Whole cell Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats and produces tachyzoites (actively proliferating trophozoites) and eventually bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis in which the maternal infection is transmitted during pregnancy can produce blindness or mental retardation in the newborn.