SSX2IP

ArtNr	18-272-198503
Hersteller	GENWAY
Menge	0,05 mg
Typ	Antibody
Applikationen	ICC, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-51CB98
Similar products	18-272-198503
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Genway ID:	GWB-51CB98
Isotype:	IgG
Immunogen:	Synthetic peptide: SYTNSHVEKDDLP
Positive Control:	Human heart lysate
Target:	SSX2IP
Concentration:	0. 5 mg/ml
Purification Note:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Storage
Buffer:	Tris-saline pH 7. 3 containing 0. 5% BSA and 0. 02% sodium azide
Application Note:	For ELISA (peptide): antibody detection limit dilution 1:16 000. For ICC/IF: Use at 1:100. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor RAB3IP and a novel nuclear protein SSX2IP.
Function:	Belongs to an adhesion system which plays a role in the organization of homotypic interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity).
Subunit:	Interacts with afadin and alpha-actinin (By similarity). Interacts with SSX2 and SSX3. Does not interact with SSX1 and SSX4.
Subcellular Location:	Cell junction adherens junction (By similarity). Nucleus. Note=Not found at cell-matrix AJs (By similarity).
Tissue Specificity:	Widely expressed with the highest expression in brain intermediate expression in kidney testis spinal cord liver heart lung skeletal muscle ovary fetal liver and fetal brain and little to no expression in pancreas and spleen. All specific brain regions showed intermediate to high expression with highest expression in amygdala. Also expressed in fetal tissues mainly in liver and brain.
Domain:	Both the N-terminal (up to position 79) and the C-terminal (from position 304) sequences are required for interaction with SSX2.

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Menge: 0,05 mg

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Lieferung vsl. bis 25.09.2025

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