Hepatocyte nuclear factor 4-gamma

GWB-D86E8E

Transcription factor. Has a lower transcription activation potential than HNF4-alpha.

Expressed in pancreas kidney small intestine and testis. Weakly expressed in colon. Not expressed in liver skeletal muscle lung placenta brain heart peripheral blood ovary prostate thymus and spleen.

Contains 1 nuclear receptor DNA-binding domain. [1] Ozeki T. Takahashi Y. Nakayama K. Funayama M. Nagashima K. Kodama T. and Kamataki T. Hepatocyte nuclear factor-4 alpha/gamma and hepatocyte nuclear factor-1 alpha as causal factors of interindividual difference in the expression of human dihydrodiol dehydrogenase 4 mRNA in human livers[2] Wisely G. B. Miller A. B. Davis R. G. Thornquest A. D. Jr. Johnson R. Spitzer T. Sefler A. Shearer B. Moore J. T. et al. Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids[3] Drewes T. Senkel S. Holewa B. and Ryffel G. U. et al. Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes[4] Drewes T. Senkel S. Holewa B. Ryffel G. U. Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes. [5] Plengvidhya N. Antonellis A. Wogan L. T. Poleev A. Borgschulze M. Warram J. H. Ryffel G. U. Krolewski A. S. Doria A. Hepatocyte nuclear factor-4gamma: cDNA sequence gene organization and mutation screening in early-onset autosomal-dominant type 2 diabetes. [6] Nusbaum C. Mikkelsen T. S. Zody M. C. Asakawa S. Taudien S. Garber M. Kodira C. D. Schueler M. G. Shimizu A. Whittaker C. A. et al. DNA sequence and analysis of human chromosome 8. [7] Wisely G. B. Miller A. B. Davis R. G. Thornquest A. D. Jr. Johnson R. Spitzer T. Sefler A. Shearer B. Moore J. T. Miller A. B. et al. Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids.