C-X-C chemokine receptor type 6

C-terminal domain of human. Synthetic peptide - KLH conjugated.
Uses: IHC (16 ug/ml) (Optimal dilution to be determined by the researcher)

Membrane; multi-pass membrane protein.

Belongs to the G-protein coupled receptor 1 family [view classification]. [1] Nanki T. Shimaoka T. Hayashida K. Taniguchi K. Yonehara S. and Miyasaka N. Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis[2] Aust G. Kamprad M. Lamesch P. and Schmucking E. et al. CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves\' disease (GD)[3] Blaak H. Boers P. H. Gruters R. A. Schuitemaker H. van der Ende M. E. and Osterhaus A. D. CCR5 GPR15 and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia[4] Wagsater D. and Dimberg J. et al. Expression of chemokine receptor CXCR6 in human colorectal adenocarcinomas[5] Shimaoka T. Nakayama T. Fukumoto N. Kume N. Takahashi S. Yamaguchi J. Minami M. Hayashida K. Kita T. Ohsumi J. et al. Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells[6] Deng H. K. Unutmaz D. Kewalramani V. N. Littman D. R. Expression cloning of new receptors used by simian and human immunodeficiency viruses. [7] Liao F. Alkhatib G. Peden K. W. C. Sharma G. Berger E. A. Farber J. M. STRL33 A novel chemokine receptor-like protein functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. [8] Loetscher M. Amara A. Oberlin E. Brass N. Legler D. F. Loetscher P. D\' Apuzzo M. Meese E. U. Rousset D. Virelizier J. L. et al. TYMSTR a putative chemokine receptor selectively expressed in activated T cells exhibits HIV-1 coreceptor function. [9] An P. Winkler C. O\' Brien S. J. The influence of a STRL33 mutant on the course of HIV-1 infection. [10] Kopatz S. A. Aronstam R. S. Sharma S. V. cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www. cdna. org).