G-protein coupled receptor

GWB-360CF0

Membrane; multi-pass membrane protein (By similarity). Summary: G protein-coupled receptors (GPCRs or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [supplied by OMIM]. [1] Lee D. K. Nguyen T. Lynch K. R. Cheng R. Vanti W. B. Arkhitko O. Lewis T. Evans J. F. George S. R. and O\' Dowd B. F. Discovery and mapping of ten novel G protein-coupled receptor genes[2] Lee D. K. Nguyen T. Lynch K. R. Cheng R. Vanti W. B. Arkhitko O. Lewis T. Evans J. F. George S. R. and O\' Dowd B. F. Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23[3] Ina K. Urakawa I. Mizutani S. Okazaki H. Probable G-protein coupled receptor.