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Rabbit A\&#039, Muscarinic M1 Rec.

Rabbit A\&#039, Muscarinic M1 Rec.

ArtNr	18-511-244142
Hersteller	GENWAY
Menge	0,1 ml
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Cardiovascular Research Hypertension Primary Antibodies
Typ	Antibody
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-FD02D3
Similar products	18-511-244142
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Genway ID:	GWB-FD02D3
Host Animal:	Rabbit
Immunogen:	A peptide analogue of the carboxyl terminal of the Muscarinic M1 receptor covalently attached to a carrier protein. .
Specificity:	Muscarinic M1 Receptor (a. a. 451-460)
Specificity:	Specific for Muscarinic M1 Receptor (carboxyl terminal) (a. a. 451-460). This antisera has been characterized by Western blotting ELISA and cell staining techniques. Cross-re
Activity:	M1 Muscarinic Receptor (451-460) 100% M1 Muscarinic Receptor 60% M2 Muscarinic Receptor (457-466) 0% M2 Muscarinic Receptor 0% M3 Muscarinic Receptor (580-589) 0% M3 Muscarinic Receptor 0% M4 Muscarinic Receptor (469-478) 0% M4 Muscarinic Receptor 0% M5 Muscarinic Receptor (519-531) 0% M5 Muscarinic Receptor 0%
Type of Product:	Polyclonal Antibodies for Neuroscience
Concentration:	Not determined.
Buffer:	Not applicable. Applications Notes : Suitable for immunocytochemical and western immunoblotting detection of the receptor. Has been found to stain PLP fixed rat brain sections known to express the muscarinic M1 receptor using ABC techniques at a dilution of 1:5 000. Western immunoblots using whole rat brain homogenerate has been successful at a dilution of 1:800. Each laboratory should determine an optimum working titer for use in its particular application. Rabbit A\' Muscarinic M1 Rec. . Rabbit Antibody to Muscarinic M1 Receptor (a. a. 451-460)
Function:	The muscarinic acetylcholine receptor mediates various cellular responses including inhibition of adenylate cyclase breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subunit:	Interacts with GPRASP2.
Subcellular Location:	Cell membrane; Multi-pass membrane protein. Cell junction synapse postsynaptic cell membrane; Multi-pass membrane protein.
Similarity:	Belongs to the G-protein coupled receptor 1 family [view classification].

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