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Rabbit anti Urokinase

Rabbit anti Urokinase

Catalytic
ArtNr	18-511-244804
Hersteller	GENWAY
Menge	1 mg
Kategorie	Oncology Antibodies Western Blot ELISA Cardiovascular Research Atherosclerosis Primary Antibodies By Organ Testicular & Prostate Cancer
Typ	Antibody
Applikationen	WB, ELISA
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-24B3D4
Similar products	18-511-244804
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Genway ID:	GWB-24B3D4
Host Animal:	Rabbit
Immunogen:	Native human Urokinase
Specificity:	Urokinase
Specificity:	Human Urokinase
Type of Product:	Polyclonal Antibodies to Enzymes
Concentration:	14. 4mg/ml (OD280nm E0. 1% = 1. 36)
Buffer:	0. 05M Sodium phosphate 0. 1M Sodium chloride 1mM EDTA pH 6. 6Applications Notes : Suitable for use in ELISA (1:10 000) and Western blot (1:1 000). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. Rabbit anti Urokinase. Rabbit Antibody to Human Urokinase
Function:	Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
Activity:	Specific cleavage of Arg-\|-Val bond in plasminogen to form plasmin.
Subunit:	Found in high and low molecular mass forms. Each consists of two chains A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. Binds LRP1B; binding is followed by internalization and degradation. Interacts with MRC2. Interacts with PLAUR.
Subcellular Location:	Secreted.
Tissue Specificity:	Expressed in the prostate gland and prostate cancers.
Ptm:	Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Pharmaceutical: Available under the name Abbokinase (Abbott). Used in Pulmonary Embolism (PE) to initiates fibrinolysis. Clinically used for therapy of thrombolytic disorders.
Similarity:	Belongs to the peptidase S1 family [view classification].
Similarity:	Contains 1 EGF-like domain.
Similarity:	Contains 1 kringle domain.
Similarity:	Contains 1 peptidase S1 domain [view classification].

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 1 mg

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Lieferung vsl. bis 11.09.2025

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