IGF-I

GWB-BF7144

16000

For long term storage the addition of 0. 09% sodium azide is recommended.

This product is specific for mouse insulin-like growth factor-1 (IGF-1). IGF-1 stimulates the proliferation of a range of cell types including bone cartilage tissue and muscle.

Phosphate buffered saline pH7. 4

For long term storage. the addition of 0. 09% sodium azide is recommended. Suggested

ELISA - 0. 5ug/mlWestern Blotting - 0. 1ug/ml - 0. 2ug/ml Summary: The somatomedins or insulin-like growth factors (IGFs) comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage but rather acted through a serum factor termed \' sulfation factor \' which later became known as \' somatomedin\' (Daughaday et al. 1972). Three main somatomedins have been characterized: somatomedin C (IGF1) somatomedin A (IGF2; MIM 147470) and somatomedin B (MIM 193190) (Rotwein 1986; Rosenfeld 2003). [supplied by OMIM]. Summary: The somatomedins or insulin-like growth factors (IGFs) comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage but rather acted through a serum factor termed \' sulfation factor \' which later became known as \' somatomedin\' (Daughaday et al. 1972 [PubMed 4550398]). Three main somatomedins have been characterized: somatomedin C (IGF1) somatomedin A (IGF2; MIM 147470) and somatomedin B (MIM 193190) (Rotwein 1986 [PubMed 3455760]; Rosenfeld 2003 [PubMed 14657423]). [supplied by OMIM].